UnicCa® surface — osteogenic potential

Why the calcium-ion surface integrates faster and resists bacterial colonisation.

  1. Balancing microbial and mammalian cell functions on calcium ion-modified implant surfaces
    Anitua E, Tejero R, Pacha-Olivenza MA, et al.
    J Biomed Mater Res Part B
    2017
  2. Sequential healing at calcium- versus calcium phosphate-modified titanium implant surfaces: an experimental study in dogs
    Favero R, Botticelli D, Antunes AA, et al.
    UnicCa® vs a calcium-phosphate surface
    Clin Implant Dent Relat Res
    2016
  3. Sequential morphometric evaluation at UnicCa® and SLActive® implant surfaces: an experimental study in the dog
    Favero V, Lang NP, Favero R, et al.
    UnicCa® vs SLActive®
    Clin Oral Implants Res
    2017

Narrow and transitional implants — transversal atrophy

Evidence for restoring narrow ridges without augmentation.

  1. Long-term follow-up of 2.5-mm narrow-diameter implants supporting a fixed prostheses
    Anitua E, Saracho J, Begoña L, Alkhraisat MH.
    Clin Implant Dent Relat Res
    2015
  2. Is alveolar ridge split a risk factor for implant survival?
    Anitua E, Alkhraisat MH.
    J Oral Maxillofac Surg
    2016

Short implants — vertical atrophy

Ten-year data on 5.5 – 8.5 mm implants as an alternative to sinus lifts and vertical grafting.

  1. Long-term retrospective evaluation of short implants in the posterior areas: clinical results after 10–12 years
    Anitua E, Piñas L, Begoña L, Orive G.
    J Clin Periodontol
    2014
  2. Five-year clinical evaluation of short dental implants placed in posterior areas: a retrospective study
    Anitua E, Orive G, Aguirre JJ, Andía I.
    J Periodontol
    2008
  3. Long-term outcomes of immediate loading of short implants: a controlled retrospective cohort study
    Anitua E, Flores J, Flores C, Alkhraisat MH.
    Int J Oral Maxillofac Implants
    2016
  4. Short dental implants as compared to maxillary sinus augmentation procedure for the rehabilitation of edentulous posterior maxilla: three-year results of a randomized clinical study
    Taschieri S, Lolato A, Testori T, et al.
    Clin Implant Dent Relat Res
    2018
  5. Transalveolar sinus floor elevation with short implants
    Anitua E, Alkhraisat MH, Piñas L, Orive G.
    Clin Oral Implants Res
    2016
  6. Transalveolar osteotomy of the mandibular canal wall for the treatment of severely atrophied posterior mandible
    Anitua E, Padilla S, Alkhraisat MH.
    J Oral Maxillofac Surg
    2017

Biological drilling

Low-speed drilling without irrigation: bone collection and primary stability.

  1. Efficacy of biologically guided implant site preparation to obtain adequate primary implant stability
    Anitua E, Alkhraisat MH, Piñas L, Orive G.
    Ann Anat
    2015
  2. Low-speed drilling without irrigation for implant site preparation
    Anitua E, et al.
    Int J Oral Maxillofac Implants
    2007

Atraumatic implant removal

Conservative explantation techniques that preserve the site for re-treatment.

  1. Conservative implant removal for the analysis of the cause, removal torque, and surface treatment of failed nonmobile dental implants
    Anitua E, Murias-Freijo A, Alkhraisat MH.
    J Oral Implantol
    2016
  2. Minimally invasive removal of nonmobile zygomatic dental implants affected by peri-implantitis and chronic sinusitis
    Anitua E, Alkhraisat MH.
    J Oral Implantol
    2017

Trans-epithelial abutments — marginal bone stability

The BioBlock® rationale: intermediate abutments and peri-implant bone.

  1. Influence of the abutment connection on marginal bone stability around implants restored on trans-epithelial abutments
    Anitua E, et al.
    Int J Oral Maxillofac Implants
    2018

Biomechanical concepts

Load distribution, implant position and long-term prosthetic outcomes.

  1. Replacement of missing posterior tooth with off-center placed single implant: long-term follow-up outcomes
    Anitua E, Murias-Freijo A, Flores J, Alkhraisat MH.
    J Prosthet Dent
    2020
  2. Biomechanical considerations for implant-supported restorations
    Anitua E, et al.
    Int J Periodontics Restorative Dent
    2010

Endoret® (PRGF) regenerative technology

Plasma rich in growth factors: biology, antibacterial effect, socket healing and quality of life. Endoret® equipment is available through Integra on request.

  1. Plasma rich in growth factors promotes bone tissue regeneration by stimulating proliferation, migration, and autocrine secretion in primary human osteoblasts
    Anitua E, Tejero R, Zalduendo MM, Orive G.
    J Periodontol
    2013
  2. Morphogen and proinflammatory cytokine release kinetics from PRGF-Endoret fibrin scaffolds: evaluation of the effect of leukocyte inclusion
    Anitua E, Zalduendo MM, Prado R, Alkhraisat MH, Orive G.
    J Biomed Mater Res A
    2015
  3. Fibroblastic response to treatment with different preparations rich in growth factors
    Anitua E, et al.
    Cell Prolif
    2009
  4. Antibacterial effect of plasma rich in growth factors (PRGF-Endoret) against Staphylococcus aureus and Staphylococcus epidermidis strains
    Anitua E, Alonso R, Girbau C, et al.
    Clin Exp Dermatol
    2012
  5. Clinical, radiographical, and histological outcomes of plasma rich in growth factors in extraction socket: a randomized controlled clinical trial
    Anitua E, Murias-Freijo A, Alkhraisat MH, Orive G.
    Clin Oral Investig
    2015
  6. Adjunctive use of plasma rich in growth factors for improving alveolar socket healing: a systematic review
    Del Fabbro M, Panda S, Taschieri S.
    J Evid Based Dent Pract
    2019
  7. Bilateral sinus elevation evaluating plasma rich in growth factors technology: a report of five cases
    Anitua E, Prado R, Orive G.
    Clin Implant Dent Relat Res
    2012
  8. Plasma rich in growth factors improves patients' postoperative quality of life in maxillary sinus floor augmentation: preliminary results of a randomized clinical study
    Del Fabbro M, Corbella S, Ceresoli V, Ceci C, Taschieri S.
    Clin Implant Dent Relat Res
    2015
  9. The efficacy of plasma rich in growth factors for the treatment of alveolar osteitis: a randomised controlled trial
    King EM, Cerajewska TL, Locke M, et al.
    J Oral Maxillofac Surg
    2018
  10. Autologous plasma rich in growth factors in the prevention of severe bleeding after teeth extractions in patients with bleeding disorders: a controlled comparison with fibrin glue
    Cocero N, Pucci F, Messina M, et al.
    Blood Transfus
    2015
  11. Comparison of intra-articular injection of plasma rich in growth factors versus hyaluronic acid following arthroscopy in the treatment of temporomandibular dysfunction: a randomised prospective study
    Fernández-Ferro M, Fernández-Sanromán J, Blanco-Carrión A, et al.
    J Craniomaxillofac Surg
    2017
  12. Plasma rich in growth factors (PRGF) and leukocyte-platelet rich fibrin (L-PRF): comparison of growth-factor release and biological effect on osteoblasts
    Baca-Gonzalez L, et al.
    Int J Implant Dent
    2022
BTI Scientific Dossier (English, 118 pages)

Full compilation of BTI's implantology and regenerative-medicine literature — sent to registered dentists on request.

Reprints are the publishers' copyrighted material and are shared for professional reference only. Integra does not publish comparative claims against other implant brands.