BTI Biotechnology Institute founded in Vitoria-Gasteiz, Spain, by Dr. Eduardo Anitua
of profits reinvested in research and development
indexed scientific articles published by the group
countries with BTI international medical patents
countries where BTI implants are placed
The surface, under the microscope
UnicCa® is the surface of BTI implants: a chemical modification with calcium ions over a triple-roughness topography. It is not a calcium-titanate nor a calcium-phosphate / hydroxyapatite coating.
BTI UnicCa® is the first implant system on the market awarded the CleanImplant Foundation Trusted Quality Mark (2017 – 2026), an independent guarantee of the purity of its materials and surface.
The topography changes along the implant so each area suits the tissue and the biomechanical need it meets.
Enhances marginal tissue retention and reduces bacterial colonisation where the implant meets the soft tissue.
Allows bone anchorage outside the threads for primary and secondary stability.
Guides bone growth between the threads while maintaining the implant's mechanical properties.
Certified, audited, traceable
BTI UnicCa® was the first implant system to receive the quality seal of the CleanImplant Foundation, which independently evaluates and certifies the surface purity of dental implants.
Implants and prosthetic components are CE-certified with declarations of conformity available for every product family. Integra provides the documentation for your practice records on request.
Integra records the BTI batch of every unit it ships, so recalls, warranty and patient records are traceable from the manufacturer to your chair.
What the published work covers
A selection of the themes in BTI's scientific dossier. Integra shares the full dossier and the reprints with registered dentists.
In-vitro and in-vivo work on the calcium-modified surface: protein adsorption, platelet activation and bone-to-implant contact compared with conventional roughened surfaces.
Long-term series on 5.5 – 8.5 mm and Ø3.3 implants as an alternative to bone augmentation in atrophic ridges.
Clinical follow-ups of the BioBlock® approach: marginal bone stability around implants restored on intermediate abutments.
Low-speed drilling without irrigation for autologous bone collection and controlled osteotomy temperature.
Independent CleanImplant Foundation analysis of production implants for particle and organic contamination.
Scientific claims are the manufacturer's, supported by its published literature. Integra does not publish comparative claims against other implant brands.